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14 principal systems engineer jobs found

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Onsite principal systems engineer Massachusetts
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OT
Apr 09, 2026
Contractor
Sr. Engineer, Device Development - CONTRACT
Ocular Therapeutix Bedford, MA, USA
Ocular Therapeutix, Inc. (NASDAQ:OCUL) is a biopharmaceutical company focused on the formulation, development, and commercialization of innovative therapies for diseases and conditions of the eye using its proprietary bioresorbable hydrogel-based formulation technology, ELUTYX™. Ocular Therapeutix has built a robust product pipeline of drug delivery solutions developed to reduce the complexity and burden of the current standard of care and position itself to become a leader in the ophthalmic space. Outside of the ophthalmic realm and behind the doors of our headquarters in Bedford, MA, we strive to build a strong culture where employees can flourish and achieve their career goals. We encourage out of the box thinking, cross-functional collaboration, and creativity. Position Summary: This position will serve the role of medical device development engineer within Pharmaceutical Development. Experienced engineer who executes technical development of drug delivery medical devices...
OT
Apr 09, 2026
Full time
Manufacturing Engineer I
Ocular Therapeutix Bedford, MA, USA
Ocular Therapeutix, Inc. (NASDAQ:OCUL) is a biopharmaceutical company focused on the formulation, development, and commercialization of innovative therapies for diseases and conditions of the eye using its proprietary bioresorbable hydrogel-based formulation technology, ELUTYX™. Ocular Therapeutix has built a robust product pipeline of drug delivery solutions developed to reduce the complexity and burden of the current standard of care and position itself to become a leader in the ophthalmic space. Outside of the ophthalmic realm and behind the doors of our headquarters in Bedford, MA, we strive to build a strong culture where employees can flourish and achieve their career goals. We encourage out of the box thinking, cross-functional collaboration, and creativity. Position Summary : We are seeking a motivated Engineer to join the MSAT team as a Manufacturing Engineer I. The individual will join a team in the clinical and commercial development of the processes used to...
WC
Apr 09, 2026
Full time
Principal, Industrial Engineer
Waters Corporation Milford, MA, USA
Overview Waters Corporation is seeking a results-driven Sr. Principal, Industrial Engineer with a solid background in manufacturing, responsible for developing, implementing, and improving processes to ensure a safe environment, efficient production, high product quality, and cost-effectiveness. This role involves working across multiple departments, including production, quality, logistics, and supply chain-to ensure smooth, cost-effective operations while maintaining high standards of quality and safety. It requires a strategic thinker with hands-on experience in process optimization, lean manufacturing, and systems integration. The Industrial Engineer is responsible for analyzing, designing, and optimizing systems and processes to improve efficiency, reduce waste, and increase productivity. They will also coordinate special projects related to plant layouts, cost savings and product improvements as required, applying quality and continuous Improvement tools....
WC
Apr 09, 2026
Full time
Principal, Industrial Engineer
Waters Corporation Milford, MA, USA
Overview Waters Corporation is seeking a results-driven Principal, Industrial Engineer with a solid background in manufacturing, responsible for developing, implementing, and improving processes to ensure a safe environment, efficient production, high product quality, and cost-effectiveness. This role involves working across multiple departments, including production, quality, logistics, and supply chain-to ensure smooth, cost-effective operations while maintaining high standards of quality and safety. It requires a strategic thinker with hands-on experience in process optimization, lean manufacturing, and systems integration. The Industrial Engineer is responsible for analyzing, designing, and optimizing systems and processes to improve efficiency, reduce waste, and increase productivity. They will also coordinate special projects related to plant layouts, cost savings and product improvements as required, applying quality and continuous Improvement tools. Responsibilities...
QE
Apr 02, 2026
Full time
Principal Mechanical Engineer
QuEra Computing, Inc. Boston, MA, USA
Principal Mechanical Engineer About Us We are building scalable, fault-tolerant neutral atom quantum computers that harness the power of atomic physics, precision engineering, and advanced control systems. Our interdisciplinary team combines quantum scientists, optical mechanical and electrical engineers, and software developers to push the boundaries of what's physically possible. About the Role We are seeking a Principal Mechanical Engineer to lead the mechanical system design, system engineering, and infrastructure architecture that enable high-fidelity, scalable neutral atom quantum systems. This role will own key aspects of system design and integration - from mechanical and thermal stability to automated alignment and digital design workflows - ensuring that our hardware meets the demands of world-class quantum performance. You will be responsible for end-to-end ownership of mechanical design and integration, partnering closely with physics, optical, and controls...
LS
Jan 16, 2026
Full time
Staff / Principal Mechanical Engineer
Lila Sciences Cambridge, MA, USA
Your Impact at Lila Lila Sciences is seeking an experienced Staff/Principal Mechanical Engineer to join our Hardware & Controls Engineering team. The specific title (Staff or Principal) will be determined based on experience level and expertise. As a key technical leader, you'll leverage your deep expertise to design and engineer components for workcell robotics, mechanical systems, and automation across life science and physical science domains. You'll collaborate with experimental scientists, AI/ML scientists, software/controls engineers, and process/automation engineers to lead complex projects, guide multidisciplinary teams, and deliver state-of-the-art automation solutions. What You'll Be Building Lead the design and implementation of bench-scale robotics and mechanical systems for sophisticated automation in life science and physical science applications. Design innovative pneumatic, electro-mechanical, and optical solutions for advanced robotic workcells used in...
nV
Sep 11, 2025
Full time
R&D Electrical Engineer
nVent MA, USA
We're looking for people who put their innovation to work to advance our success - and their own. Join an organization that ensures a more secure world through connecting and protecting our customers with inventive electrical solutions. The Electrical Products Group was recently purchased from Avail Infrastructure Solutions by nVent Electric plc ("nVent") and consists of three business units, Enclosure Systems, Switchgear Systems and Bus Systems. As a part of nVent, the Electrical Products Group is a leading provider of infrastructure solutions, designed to help ensure safe and reliable electrical operations primarily in the infrastructure vertical, including power utilities and data centers. We are seeking a skilled R&D Electrical Engineer to join our team. In this role, you will be responsible for a wide range of engineering functions involving the design and development of high voltage Bus System products and develop new and improved designs. As industry standards continue...
SC
Apr 09, 2026
Full time
Senior Engineer - Tooling
$123,000 - $144,000 yearly
SMC Corporation of America MA, USA
About Us: SMC Ltd. is a globally recognized premium supplier to the medical market with locations throughout the world. People committed to speed, technology, and exceptional performance are the cornerstone of our organization. Comprised of dedicated people and decades of manufacturing experience, we have continued to experience strong growth and currently have outstanding career opportunities for equally dedicated people. Job Description: The Senior Tooling Engineer is responsible for leading the design, development, qualification, and continuous improvement of injection molds and related tooling within a high-volume plastics manufacturing environment. This role ensures that tooling meets performance, quality, and cost targets while supporting efficient, stable, and scalable molding operations. The engineer acts as a technical authority on mold design, materials, processing, and troubleshooting. Essential Job Duties and Responsibilities Lead the design, specification,...
RM
Mar 27, 2026
Full time
Manufacturing Engineer II
Rapid Micro Biosystems Lowell, MA, USA
Winning the race to bring new healthcare products safely to a waiting world drives Rapid Micro Biosystems (RMB) to combine today's innovative technologies as never before. Your career at RMB puts you at the center of diverse global teams that span robotics, AI, Machine Learning, imaging, microbiology, and more, re-shaping how urgently needed pharmaceuticals are made, tested, and released for decades to come. The sky's the limit. Careers at RMB are fast-moving, with the high growth you'd expect from a world leader in microbiology automation. Advancement at RMB affords an opportunity to achieve your personal goals and develop your passions, in an inclusive environment where every employee has the resources and opportunities to hone their skills. You'll do more, learn more, and have the ability to make a profound impact on our business. The Manufacturing Engineer II will have responsibility to support the day-to-day operation of automated production equipment at RMB, Lowell. This...
DR
Mar 13, 2026
Full time
Site Engineer II
Digital Realty Needham, MA, USA
Job Description Position Title: Site Engineer II Your role The Site Engineer II position is a contributing member to the site level Data Center Operations team assigned to one or more of our data center properties reporting directly to the Manager Engineering Operations. The Site Engineer II will have experience in mission critical infrastructure, including Generators, UPS Systems, HVAC Systems, Fire/Life Safety Systems, BMS Systems, and CMMS systems. It is expected that the Site Engineer I candidate has expertise in either electrical work or mechanical work and it would be expected that he/she would be competent in the area of non expertise. The responsibilities of the Site Engineer II are: to contribute to the daily site operation, including creation and modification of site operating procedures, contribute to creation of change management tickets, creation of timely incident reporting, site maintenance and repairs/inspections to help ensure Digital Realty's data center...
TM
Feb 22, 2026
Full time
Director of Electrical & Systems Engineering
TransMedics Andover, MA, USA
Job Description: POSITION SUMMARY The Director of Electrical & Systems Engineering will plan, design, and oversee the electrical and biomedical infrastructure of our organization to ensure those designs are implemented effectively while meeting the needs of the business and adhering to industry standards. This role also involves leading and mentoring a team of electrical and biomedical engineers, developing long-range plans, strategies, and driving top-level company objectives. This position is onsite 5 days a week. RESPONSIBILITIES Responsible for the electrical architecture, design and testing for the Next Generation Organ Care System while ensuring compliance with project requirements and regulatory standards. Provide leadership, oversight and guidance to internal and external design teams for new and legacy products, complaint investigations, and obsolescence. Possess a hands-on approach to developing electrical engineering strategies, prototypes and designs for...
SP
Feb 09, 2026
Full time
Senior Associate, Medical Device / Combination Product Engineer
$102,500 - $125,000 yearly
Sun Pharmaceutical Industries Billerica, MA, USA
Sun Pharma is the world's fourth largest generics company with presence in Specialty, Generics and Consumer Healthcare products. Supported by more than 40 manufacturing facilities, we provide high-quality medicines, trusted by healthcare professionals and patients, to more than 100 countries across the globe. Over the last two decades, Sun Pharma has established itself as a leading player in the generics market in the U.S., and we are rapidly ramping up our presence in the specialty branded market with a focus on dermatology, ophthalmology and onco-dermatology. Job Summary: This position provides mechanical and electromechanical engineering for sustaining engineering support for existing medical products as well as new projects. Area Of Responsibility: Provide support for existing products, product investigations, and analysis to determine root cause and appropriate resolution of product issues, and support customer requirements Prepare and maintain all necessary product...
UC
Feb 07, 2026
Intern
Summer Internship Structural Engineer 2026
Unistress Corporation Pittsfield, MA, USA
Application Instructions Dear Applicant, Thank you for your interest in the Unistress Corp. job opportunity. To ensure a smooth application process, please follow the instructions below: Answer Questions: Please take the time to answer the provided questions thoroughly and accurately. These questions are designed to gather additional information about your skills, experience, and qualifications relevant to the position. Take this opportunity to highlight your strengths and demonstrate why you are a suitable candidate. Work History: Fill out the work history section with detailed information about your previous employment. Include the company name, job title, duration of employment, and a brief description of your responsibilities and achievements. Emphasize your relevant experiences that align with the requirements of the position you are applying for. Educational History: Provide accurate details of your educational background. Include the names of institutions...
MT
Nov 22, 2025
Full time
Mechanical Engineering, Principal
MACOM Technology Solutions Holdings Lowell, MA, USA
MACOM designs and manufactures semiconductor products for Data Center, Telecommunication and Industrial and Defense applications. Headquartered in Lowell, Massachusetts, MACOM has design centers and sales offices throughout North America, Europe and Asia. MACOM is certified to the ISO9001 international quality standard and ISO14001 environmental management standard. MACOM has more than 75 years of application expertise with multiple design centers, Si, GaAs, and InP fabrication, manufacturing, assembly and test, and operational facilities throughout North America, Europe, and Asia. Click here to view our facilities. https://www.macom.com/. In addition, MACOM offers foundry services that represents a key core competency within our business. MACOM sells and distributes products globally via a sales channel comprised of a direct field sales force, authorized sales representatives and leading industry distributors. Our sales team is trained across all of our products to give our...
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